It's like adding a new “drug.” Just because the FDA calls it an antipsychotic, and that word is printed on the box, doesn't mean it is. Reducing the dose puts you into a different "level." They’re not half as good as they were, they’re completely different. It doesn’t give you a little bit of efficacy at a low dose, “oh, it’s working a little bit—he must be a Seroquel responder—I’ll just increase the dose to get more efficacy.” Another way of saying it is this: the absence of efficacy at 250mg is in no way predictive of what might happen at 500mg, because the two doses are working at different receptors.
So, yes, 5mg Zyprexa is equal to 250mg Seroquel for psychosis, in the same way that an academic psychiatrist is like a certain Congresswoman from California: they all do nothing. pie chart, derived from affinities of receptors ripped out of the cadaverous remains of former tax attorneys. become saturated, before the next system is impacted. 250mg Seroquel has trivial D2 blockade, but Zyprexa 5mg still has some (55%).
Examples of drugs which can be used for sedation include propofol, etomidate, ketamine, fentanyl, and midazolam.
Sedation is typically used in minor surgical procedures such as endoscopy, vasectomy, or dentistry and for reconstructive surgery, some cosmetic surgeries, removal of wisdom teeth, or for high-anxiety patients.
It may not represent what happens in an actual human body when confronted with unequal distribution of drug and receptors, number, and subtypes of receptors. More accurately, there exists a certain level of binding at one receptor such that it then becomes equally likely that it goes elsewhere. Be careful: these are the equivalents for D2 blockade—for antipsychosis. So 5mg Zyprexa is more likely to treat psychosis than 250mg Seroquel.