What won't be different is that you will be followed by gun-toting Albanians, and you will almost immediately lose the back door of the hearse you're driving.
This means that you have to drive as carefully as you can (considering armed maniacs are on your tail), because every bump and crash will disturb the casket a little bit more.
This is a good reminder to keep Kate on your radar as well, since dating her has been an option for you for quite some time.
Katie "Kate" Mc Reary (Irish: Cáit Nic Ruairi) is a 28 year old character in the HD Universe and one of the love interests of Grand Theft Auto IV protagonist Niko Bellic.
Over time she has apparently become accustomed to living close to violent crime, liking Niko despite disapproving of his lifestyle. Mc Reary had an excellent relationship with Kate and was pretty much never angry at her.